CAS RN 627536-09-8

IUPAC Name: 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

Synonyms: 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

Molecular Weight (g/mol): 352.76

Molecular Formula: C17H10ClFN6

InChi Key: BERLXWPRSBJFHO-UHFFFAOYSA-N

SMILES: FC1=C(C=C(Cl)C=C1)C1=NC(NC2=CC=NC=C2)=C2N=CC=NC2=N1

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CAS: 627536-09-8 Molecular Formula: C17H10ClFN6

CAS	627536-09-8
Molecular Formula	C17H10ClFN6

MedChemExpress SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, and > 100-fold selectivity over TGF-βRII.

Molecular Weight (g/mol)	352.75
Color	Yellow-Brown
Physical Form	Solid
Chemical Name or Material	SD-208
Grade	Research
SMILES	FC1=CC=C(Cl)C=C1C2=NC3=NC=CN=C3C(NC4=CC=NC=C4)=N2
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.42%
CAS	627536-09-8
Solubility Information	DMSO : 9.09 mg/mL (25.77 mM; Need ultrasonic)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₇H₁₀ClFN₆
Formula Weight	352.75