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Tocris Bioscience™ SD 208
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Product Code. 18076012
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18076012

Brand: Tocris Bioscience™ 3269/50

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9364.50 NOK valid until 2025-12-16
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Description

Potent ATP-competitive TGF-βRI inhibitor

Potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50 = 49 nM). Displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. Exhibits anti-inflammatory and antitumor activity. Also promotes an antiglioma immune response. Ameliorates germinal matrix hemorrhage-induced neurological deficits in neonatal rats.
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Chemical Identifiers

CAS 627536-09-8
Molecular Formula C17H10ClFN6

Specifications

Quantity 50 mg
Formula Weight 352.75
Purity >98%
Molecular Weight (g/mol) 352.76
Chemical Name or Material SD 208
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