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Tocris Bioscience™ IMD 0354
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Product Code. 18075492
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18075492

Brand: Tocris Bioscience™ 2611/10

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This item is not returnable. View return policy

Description

Inhibitor of IKKβ

Inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation. Attenuates myocardial ischemia/reperfusion injury by decreasing expression of adhesion molecules ICAM-1 and P-selectin and inhibiting cytokine and chemokine production in cardiomyocytes. Induces G0/G1 cell cycle arrest and apoptosis in HMC-1 and breast cancer cells. Also antagonist at P2X1, P2X4 and P2X7 receptors (IC50 values are 19, 156 and 175 nM respectively). Inhibits platelet aggregation induced by collegen in vitro.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 978-62-1
Molecular Formula C15H8ClF6NO2

Specifications

Quantity 10 mg
Formula Weight 383.67
Purity >99%
Molecular Weight (g/mol) 383.67
Chemical Name or Material IMD 0354
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