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  5. Tocris Bioscience™ Desformylflustrabromine hydrochloride

Tocris Bioscience™ Desformylflustrabromine hydrochloride
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Product Code. 18045062
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18045062

Brand: Tocris Bioscience™ 3328/50

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This item is not returnable. View return policy

Description

Positive allosteric modulator of α4β2; also muscle-type nAChR inhibitor

Positive allosteric modulator of nicotinic α4β2 receptors; selectively increases the ionic current through α4β2 in the presence of ACh. Displays 14.7-fold selectivity for α4β2 over homomeric (α7) receptors. Moderately cytotoxic in HCT-116 cells. Also inhibits human muscle (αβεδ) and Torpedo (αβγδ) nAChRs (IC50 values are 1.0 and 0.1 μM, respectively) by binding in the ion channel.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 951322-11-5
Molecular Formula C16H22BrClN2

Specifications

Quantity 50 mg
Formula Weight 357.72
Purity >98%
Molecular Weight (g/mol) 357.72
Chemical Name or Material Desformylflustrabromine hydrochloride
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