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Tocris Bioscience™ Desformylflustrabromine hydrochloride

Description
Positive allosteric modulator of nicotinic α4β2 receptors; selectively increases the ionic current through α4β2 in the presence of ACh. Displays 14.7-fold selectivity for α4β2 over homomeric (α7) receptors. Moderately cytotoxic in HCT-116 cells. Also inhibits human muscle (αβεδ) and Torpedo (αβγδ) nAChRs (IC50 values are 1.0 and 0.1 μM, respectively) by binding in the ion channel.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 357.72 |
| Purity | >98% |
| Molecular Weight (g/mol) | 357.72 |
| Chemical Name or Material | Desformylflustrabromine hydrochloride |
Product Title
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