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STEMCELL Technologies Compound E
Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein
Brand: STEMCELL Technologies 73952
Additional Details : Weight : 0.05000kg
Description
- Compound E is a potent, cell-permeable, selective inhibitor that blocks the cleavage of both gamma-secretase and the Notch intracellular domain with similar IC50 values, ranging from 0.24 to 0.37 nM (Beher et al.; Seiffert et al.)
- Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.)
- Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.)
Specifications
| 209986-17-4 | |
| 500 μg | |
| ≥98% |
| γ-secretase inhibitor XXI | |
| C27H24F2N4O3 |