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STEMCELL Technologies Compound E
Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein
3159.74 NOK - 5654.26 NOK
Specifications
| CAS | 209986-17-4 |
|---|---|
| Synonym | γ-secretase inhibitor XXI |
| Molecular Formula | C27H24F2N4O3 |
| Purity | ≥98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17110302
|
STEMCELL Technologies
73954 |
1 mg |
5654.26 NOK
1mg |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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|
17100302
|
STEMCELL Technologies
73952 |
500 μg |
3159.74 NOK
500µg |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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Description
- Compound E is a potent, cell-permeable, selective inhibitor that blocks the cleavage of both gamma-secretase and the Notch intracellular domain with similar IC50 values, ranging from 0.24 to 0.37 nM (Beher et al.; Seiffert et al.)
- Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.)
- Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.)
Specifications
| 209986-17-4 | |
| γ-secretase inhibitor XXI | |
| C27H24F2N4O3 | |
| ≥98% |