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Tocris Bioscience™ BI 78D3
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Product Code. 18075192
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18075192 50 mg 50mg
18065512 10 mg 10mg
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Product Code. 18075192

Brand: Tocris Bioscience™ 3314/50

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Description

Selective, competitive JNK inhibitor

Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 883065-90-5
Molecular Formula C13H9N5O5S2

Specifications

Quantity 50 mg
Formula Weight 379.37
Purity >99%
Molecular Weight (g/mol) 379.365
Chemical Name or Material BI 78D3
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