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  5. Tocris Bioscience™ WZB 117

Tocris Bioscience™ WZB 117
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Product Code. p-7114665
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Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
Product Code. Quantity unitSize
18766946 25 mg 25mg
18786606 5 mg 5mg
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Product Code. 18766946

Brand: Tocris Bioscience™ 6143/25

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Description

GLUT inhibitor

WZB 117 is a GLUT inhibitor (Ki(app) values are 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively). Competitive inhibitor of net glucose uptake but a noncompetitive inhibitor of sugar efflux from cells. Inhibits passive sugar transport in human erythrocytes and cancer cell lines. Attenuates erythrocyte 3-O-metylglucose (3MG) uptake in vitro (Ki = 6 μM). Suppresses tumor growth in a nude mouse model.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
CAS 1223397-11-2
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C20H13FO6
Formula Weight Observed MW: 368.31
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