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Tocris Bioscience™ TCS 21311

Product Code. 18004422
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10 mg
Unit Size:
10mg
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18004422 10 mg 10mg
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Product Code. 18004422 Supplier Tocris Bioscience™ Supplier No. 4221/10

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Description

Potent JAK3 inhibitor. Also inhibits GSK-3β and PKC

TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). Selective for JAK3 over JAK1, JAK2 and TYK2 (IC50 values are 1017, 2550 and 8055 nM respectively). Also inhibits GSK-3β, PKCα and PKCθ (IC50 values are 3, 13 and 68 nM respectively).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
CAS 1260181-14-3
Quantity 10 mg
Target JAK Kinase Inhibitors
Molecular Formula C27H25F3N4O4
Purity 98%
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