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  5. Tocris Bioscience™ Talabostat Mesylate

Tocris Bioscience™ Talabostat Mesylate
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Product Code. 18739936
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50 mg
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Product Code. Quantity unitSize
18739936 50 mg 50mg
18709026 10 mg 10mg
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Product Code. 18739936

Brand: Tocris Bioscience™ 3719/50

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Description

Inflammasomes Activators

Talabostat mesylate is a potent DPP IV inhibitor (IC50 values are <4, 4, 11, 310 and 560 nM at DPP4, DPP8, DPP9, DPP7 and FAP, respectively). Activates the inflammasome sensor protein NLRP1b and selectively triggers pyroptosis in monocytes and macrophages. Induces immune-mediated tumor regression in multiple mouse models of cancer. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material B-[(2R)-1-[(2S)-2-Amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid methanesulfonate
CAS 150080-09-4
Synonym Val-boroPro, BXCL 701
Quantity 50 mg
Molecular Formula C9H19BN2O3.CH3SO3H
Formula Weight 310.18
Purity 98%
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