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STEMCELL Technologies Refametinib

Product Code. 17150212
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 17150212

Brand: STEMCELL Technologies 73374

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This item is not returnable. View return policy

Description

MEK/ERK Pathway Inhibitor; Inhibits MEK1 and MEK2

  • Refametinib is an inhibitor of both mitogen-activated protein kinase kinases 1 (MEK1) and 2 (MEK2) with IC50 values of 19 and 47 nM respectively
  • It binds in an allosteric site adjacent to the ATP pocket and is selective for MEK1/2 versus 205 other kinases (Iverson et al.)

Specifications

CAS 923032-37-5
Synonym BAY-86-9766; RDEA119
Quantity 10 mg
Molecular Formula C19H20F3IN2O5S
Purity ≥95%
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