missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ Pyr 10

Tocris Bioscience™ Pyr 10
GREENER_CHOICE

Product Code. 18768946
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18768946 50 mg 50mg
18758536 10 mg 10mg
2 options
This item is not returnable. View return policy

Product Code. 18768946

Brand: Tocris Bioscience™ 6941/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Selective TRPC3 inhibitor

Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
CAS 1315323-00-2
Quantity 50 mg
Target TRPC Channel Blockers
Molecular Formula C18H13F6N3O2S
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.