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Thermo Scientific™ Opti-Link™ Carboxylate-Modified Particles
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Control sensitivity, specificity and stability with various acid content available within Thermo Scientific™ Opti-Link™ Carboxylate-Modified Particles. Particles contain carboxylic acid groups for covalent coupling and can be used directly from the bottle in a variety of applications.
- Parking area combines surface area and acid content to give you the surface acid distribution that is useful for assay optimization
- Surface area per gram of a particle varies inversely with the particle diameter
- Acid content refers to the titrated milliequivalents per gram (mEq/g) and is weight-based
- For most applications, particles can be used directly from the bottle without any pre-cleaning
- Proprietary anionic surfactant does not interfere with binding of proteins nor cause proteins to desorb from particle surfaces or cause proteins to desorb from particle surfaces
- Various surface acid concentrations available to help optimize reagent development efforts
- Particles have been used in and are equally successful in molecular biology and research applications
Parking Area Properties
- Low Acid Content—60–100 Parking Area—Hydrophobic surface, more colloidally stable than plain polystyrene
- Medium Acid Content—35–59 Parking Area—Hydrophobic and hydrophilic areas; good colloidal stability and good covalent coupling
- High Acid Content—10–34 Parking Area—Hydrophilic surface; excellent colloidal stability; excellent covalent coupling
Recommended for:
- Clinical diagnostics
- Molecular biology
- Nephelometric, turbidimetric and slide agglutination assays
Note:
When using Opti-Link particles, ask about our Microparticle Reagent Optimization manual, which outlines our reagent development strategy. This manual includes validated binding, coupling and particle reagent optimization protocols.
Specifications
Specifications
| Additive | Proprietary anionic surfactant |
| Certifications/Compliance | Includes Certificate of Analysis |
| Concentration | 4% |
| Content And Storage | Unless otherwise stated, refrigerate (2° to 8°C) product when not in use but do not freeze. Store upright and keep bottle tightly sealed. Mix product with gentle inversion by hand or vortex mixer. |
| Description | Particles that contain carboxylic acid groups for covalent coupling and that can be used in a variety of applications. |
| Color | White or Colorless |
| For Use With (Application) | Covalent Coupling |
| Material | Polystyrene Sulfate |
| Product Type | Specialty Particles |
| Includes | Package Insert Sheet containing Certicate of Analysis |
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Certificates
Certificates
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