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Tocris Bioscience™ NSC 74859
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Product Code. 30001662
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001662

Brand: Tocris Bioscience™ 4655/50

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This item is not returnable. View return policy

Description

Selective STAT3 inhibitor

NSC 74859 selectively inhibits STAT3 DNA-binding activity in vitro (IC50 values are 86, 160, and >300 μM for STAT3-STAT3, STAT1-STAT3 and STAT1-STAT1 DNA-binding activity respectively). NSC 74859 blocks growth and induces apoptosis preferentially in tumor cells that contain persistently active STAT3 in vitro and arrests tumor growth in a murine xenograft model in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 501919-59-1
Molecular Formula C16H15NO7S

Specifications

Quantity 50 mg
Formula Weight 365.36
Purity >98%
Molecular Weight (g/mol) 365.356
Chemical Name or Material NSC 74859
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