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Tocris Bioscience™ NSC 663284

Product Code. 18075462
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Quantity:
10 mg
Unit Size:
10mg
Product Code. Quantity unitSize
18075462 10 mg 10mg
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Product Code. 18075462

Brand: Tocris Bioscience™ 1867/10

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3051.50 NOK valid until 2026-03-31
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Description

Potent, selective Cdc25 phosphatase inhibitor

Potent, selective inhibitor of Cdc25 dual specificity phosphatases (Ki values are 29, 95 and 89 nM for human Cdc25A, Cdc25B2 and Cdc25C respectively); > 20- and > 450-fold selective over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC50 = 0.2 - 35 μM).
TRUSTED_SUSTAINABILITY

Specifications

CAS 383907-43-5
Quantity 10 mg
Molecular Formula C15H16ClN3O3
Formula Weight 321.76
Purity >99%
Molecular Weight (g/mol) 321.76
Chemical Name or Material NSC 663284
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