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Tocris Bioscience™ MRK 016
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Product Code. 18095582
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18095582 10 mg 10mg
18005882 50 mg 50mg
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Product Code. 18095582

Brand: Tocris Bioscience™ 3817/10

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Description

α5-selective GABAA inverse agonist

GABAA receptor inverse agonist selective for the α5-subtype (EC50 = 3 nM). Exhibits affinity at benzodiazepine binding site of recombinant human GABAA receptors (Ki values are 0.77 nM, 0.83 nM, 0.85 nM and 1.4 nM for α3-, α1-, α2-, and α5-containing respectively). Increases long-term potentiation (LTP) in mouse hippocampal slices. Exhibits no anxiogenic or proconvulsant activity.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 783331-24-8
Molecular Formula C17H20N8O2

Specifications

Quantity 10 mg
Formula Weight 368.39
Purity >98%
Molecular Weight (g/mol) 368.401
Chemical Name or Material MRK 016
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