missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Phenylpropanoids and polyketides
  6. Tetracyclines
  7. 18064532

Minocycline hydrochloride, Tocris Bioscience™

Catalog Number 18064532
Click to view available options
Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Antibiotic. Displays neuroprotective effects

Minocycline hydrochloride is a tetracycline antibiotic. Displays neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. Acts as a matrix metalloproteinase (MMP) inhibitor; attenuates disease severity in mouse models of multiple sclerosis. Orally active and brain penetrant. Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), (S)-(+)-Dimethindene maleate (Cat.No. 1425) and human leukemia inhibitory factor.

For more information about how Minocycline hydrochloride may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .

CAS 13614-98-7
Molecular Formula C23H28ClN3O7
MDL Number MFCD00083669
Quantity 50 mg
Synonym minocycline hydrochloride, minocycline hcl, minomycin, minocin, minocycline chloride, arestin, vectrin, minomax, periocline, tri-mino
InChI Key KDLQIOPKJDNQIM-WUURTAMISA-N
SMILES [H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(O)=C4C(O)=C3C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O)N(C)C
IUPAC Name hydrogen (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride
Molecular Weight (g/mol) 493.94
PubChem CID 54685925
Formula Weight 493.94
Percent Purity >98%
Chemical Name or Material Minocycline hydrochloride
Show More Show Less
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.

Cancel missing translation for 'submit'