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  5. Tocris Bioscience™ KG 5

Tocris Bioscience™ KG 5
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Product Code. 18780518
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18780518 10 mg 10mg
18780789 50 mg 50mg
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Product Code. 18780518

Brand: Tocris Bioscience™ 5260/10

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Description

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

KG 5 is a PDGFRβ and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
CAS 877874-85-6
Quantity 10 mg
Target Raf Kinase Inhibitors
Molecular Formula C20H16F3N7OS
Formula Weight 459.45
Purity >98%
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