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Tocris Bioscience™ JNJ 10397049

Description
Selective OX2 receptor antagonist (pIC50 = 7.4 for chimeric OX2 receptors; pKB values are 5.9 and 8.5 for OX1 and OX2 receptors respectively). Shows no significant activity in a panel of over 50 other neurotransmitters and neuropeptide receptors. Achieves high level of OX2 receptor occupancy in the rat brain; exhibits sleep-promoting effects in rats.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 484.18 |
| Purity | >99% |
| Molecular Weight (g/mol) | 484.188 |
| Chemical Name or Material | JNJ 10397049 |
Product Title
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