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Tocris Bioscience™ Jasplakinolide
Description
Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ∽ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.
Specifications
Specifications
| CAS | 102396-24-7 |
| Quantity | 100 μg |
| Molecular Formula | C36H45BrN4O6 |
| Formula Weight | 709.67 |
| Purity | >97% |
| Molecular Weight (g/mol) | 709.682 |
| Chemical Name or Material | Jasplakinolide |
Product Title
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