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  5. Tocris Bioscience™ ICG 001

Tocris Bioscience™ ICG 001

Product Code. 18035112
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18035112 50 mg 50mg
18065922 10 mg 10mg
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Product Code. 18035112

Brand: Tocris Bioscience™ 4505/50

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Description

Inhibits TCF/β-catenin-mediated transcription

ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription. Selectively inhibits β-catenin/CBP interaction; displays no effect on β-catenin/p300 interaction. Exhibits growth inhibitory effects in colon carcinoma cell lines (SW480 and HCT-116 cells); also displays efficacy in Min mouse and nude mouse SW620 xenograft models.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
CAS 780757-88-2
Quantity 50 mg
Target beta-Catenin Inhibitors
Molecular Formula C33H32N4O4
Purity 0.98
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