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  5. Tocris Bioscience™ H-7 dihydrochloride

Tocris Bioscience™ H-7 dihydrochloride
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Product Code. 18094802
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18094802 10 mg 10mg
18084052 50 mg 50mg
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Product Code. 18094802

Brand: Tocris Bioscience™ 0542/10

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1576.80 NOK valid until 2026-03-31
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Description

Protein kinase inhibitor

H-7 dihydrochloride is a protein kinase inhibitor (IC50 values for inhibition of PKA, PKG, PKC and myosin light chain kinase are 3.0, 5.8, 6.0 and 97.0 μM, respectively. H-7 shows antiviral activity against influenza A (IC50 = 10 μM) in vitro. H-7 also inhibits interleukin-stimulated secretion of IgM and blocks PMA -stimulated interleukin 1β production.
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Specifications

Chemical Name or Material '±-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
CAS 108930-17-2
Assay Percent Range >99%
Quantity 10 mg
Solubility Soluble to 20mM in DMSO
Molecular Formula C14H17N3O2S.2HCl
Formula Weight Observed MW: 364.29

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