missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. STEMCELL Technologies GANT 58

STEMCELL Technologies GANT 58

Product Code. 17170302
Encompass_Preferred
Click to view available options
Quantity:
10 mg
Unit Size:
10mg
This item is not returnable. View return policy

Product Code. 17170302

Brand: STEMCELL Technologies 73984

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Hedgehog pathway inhibitor; Inhibits GLI1

  • GANT 58 inhibits the Hedgehog signaling pathway downstream of Smoothened and Suppressor of Fused (SUFU) leading to GLI1 nuclear accumulation (Joo et al.; Stanton & Peng)
  • GANT 58 demonstrates antiproliferative and antitumor activity in vivo (Beauchamp et al.; Joo et al.)
  • Reduces anchorage-independent growth in Ewing Sarcoma cells (Beauchamp et al.; Joo et al.)
  • Inhibits prostate cancer tumor growth (Lauth et al.)
  • Causes cell cycle arrest and apoptosis in acute leukemia T cells (Hou et al.)

Specifications

CAS 64048-12-0
Synonym NSC 75503
Quantity 10 mg
Molecular Formula C24H16N4S
Purity ≥98%
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.