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Tocris Bioscience™ Eeyarestatin I
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Product Code. 18014892
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Quantity:
10 mg
Unit Size:
10mg
Product Code. Quantity unitSize
18014892 10 mg 10mg
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Product Code. 18014892

Brand: Tocris Bioscience™ 3922/10

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Description

Potent inhibitor of ER-associated protein degradation and translocation

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquitinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination. Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the proapoptotic protein NOXA. Also enhances adeno-associated viral transduction in multiple cells types.
TRUSTED_SUSTAINABILITY

Specifications

CAS 412960-54-4
Quantity 10 mg
Molecular Formula C27H25Cl2N7O7
Formula Weight 630.44
Purity >98%
Chemical Name or Material Eeyarestatin I
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