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STEMCELL Technologies Compound E

Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein

Brand:  STEMCELL Technologies 73954

Additional Details : Weight : 0.05000kg

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Product Code. 17110302

  • 5654.26 NOK / 1mg
Estimated Shipment: 22-04-2024
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Description

Description

  • Compound E is a potent, cell-permeable, selective inhibitor that blocks the cleavage of both gamma-secretase and the Notch intracellular domain with similar IC50 values, ranging from 0.24 to 0.37 nM (Beher et al.; Seiffert et al.)
  • Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.)
  • Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.)
Specifications

Specifications

209986-17-4
1 mg
≥98%
γ-secretase inhibitor XXI
C27H24F2N4O3
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