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Tocris Bioscience™ Compound E

Product Code. 18776179
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Quantity:
1 mg
Unit Size:
1mg
Product Code. Quantity unitSize
18776179 1 mg 1mg
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Product Code. 18776179

Brand: Tocris Bioscience™ 6476/1

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4037.50 NOK valid until 2026-03-31
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Description

γ-secretase inhibitor; induces neuronal differentiation

Compound E is a γ-secretase and notch patchway inhibitor. Compound E enhances growth inhibition, differentiation and migration of neuroblastoma cells when used in a combination with DAPT (Cat. No. 2634) and 13-cis RA. In combination with hLIF, CHIR 99021 (Cat. No. 4423) and SB 431542 (Cat. No. 1614), Compound E accelerates the induction of a homogeneous, self-renewing primitive neuroepithelium population from hESCs. Compound E is active in vitro and in vivo.

For more information about how Compound E may be used, see our protocol:

Generation of β cells from hPSCs
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
CAS 209986-17-4
Quantity 1 mg
Molecular Formula C27H24F2N4O3
Purity 98%
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