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  5. Tocris Bioscience™ CDK8/19i

Tocris Bioscience™ CDK8/19i
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Product Code. p-7237114
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18777206

Brand: Tocris Bioscience™ 7372/10

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Description

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

CDK8/19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2.9 and 14.1 nM, respectively). CDK8/19i maintains pluripotency of mouse PSCs in culture. It induces the formation of dome-shaped colonies and upregulates Nanog-GFP reporter and endogenous Nanog expression in mouse ESCs in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
CAS 923596-52-5
Quantity 10 mg
Target Cyclin-dependent Kinase Inhibitors
Molecular Formula C14H15N5
Purity 0.98
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