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Tocris Bioscience™ BAY 41-8543, >98%

Description
Guanylyl cyclase (sGC) stimulator. Increases activity of sGC by up to 92-fold at concentrations up to 100 μM. Induces relaxation of aorta, saphenous arteries, coronary arteries and veins in vitro. Inhibits collagen-induced platelet aggregation. Promotes lipid uptake into brown adipose tissue and increases energy expenditure in mice. Induces weight loss in obese mice. Antihypertensive.
Specifications
Specifications
| Quantity | 10 mg |
| Solubility | Soluble to 10mM in DMSO with gentle warming |
| Formula Weight | 420.44 |
| Purity | >98% |
| Molecular Weight (g/mol) | 420.452 |
| Chemical Name or Material | 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamin |
Product Title
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