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ANT1/2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1710.33 NOK - 4836.10 NOK

Specifications

Antigen ANT1/2
Concentration 0.45 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16857774
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Proteintech
17796-1-AP-20UL
20 μL
1710.33 NOK
20µL
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16847774
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Proteintech
17796-1-AP-150UL
150 μL
4836.10 NOK
150µL
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Description

Description

This antibody recognizes both of ANT1 and ANT2. The predicted molecular weight of ANT1/2 protein is around 32 kDa. While 60 kDa protein can also be observed, which has been proposed as the dimmer of ANT1/2.

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintece of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
Specifications

Specifications

ANT1/2
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Rat, Mouse, Human
P05141, P12235, P48962, P51881, Q05962, Q09073
11739, 11740, 25176, 291, 292, 85333
ANT1/2 Fusion Protein Ag11956
Primary
-20°C
SLC25A4
0.45 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
2F1, AAC2, ADP,ATP carrier protein 2, ADP/ATP translocase 2, ANT 2, ANT1/2, SLC25A5, T2, T3
SLC25A4, Slc25a5
IgG
Antigen Affinity Chromatography
Antibody
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