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ANT1/2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16857774 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16857774 20 μL 20µL
16847774 150 μL 150µL
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Product Code. 16857774

Brand: Proteintech 177961AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody recognizes both of ANT1 and ANT2. The predicted molecular weight of ANT1/2 protein is around 32 kDa. While 60 kDa protein can also be observed, which has been proposed as the dimmer of ANT1/2.

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintece of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.

Specifications

Antigen ANT1/2
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SLC25A4
Gene Accession No. P05141, P12235, P48962, P51881, Q05962, Q09073
Gene Alias 2F1, AAC2, ADP,ATP carrier protein 2, ADP/ATP translocase 2, ANT 2, ANT1/2, SLC25A5, T2, T3
Gene Symbols SLC25A4, Slc25a5
Host Species Rabbit
Immunogen ANT1/2 Fusion Protein Ag11956
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11739, 11740, 25176, 291, 292, 85333
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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