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Tocris Bioscience™ Amlexanox

Description
Selective inhibitor of TANK-binding kinase 1 (TBK1) and IKKε (IC50 values are ∽1-2 μM). Displays no effect on IKKα or IKKβ at these concentrations. Reversibly lowers weight, increases insulin sensitivity, and reduces inflammation and steatosis in three mouse models of obesity. Exhibits antiallergic activity; inhibits the release of histamine from rat mast cells. Also binds to Hsp90 and inhibits C-terminal chaperone activity in vitro.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 298.29 |
| Purity | >99% |
| Molecular Weight (g/mol) | 298.30 |
| Chemical Name or Material | Amlexanox |
Product Title
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