CAS RN 955365-80-7

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Potent and selective Wee1 inhibitor

Target	Checkpoint Control Kinase Inhibitors
CAS	955365-80-7
Purity	98%
Chemical Name or Material	1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3 H-pyrazolo[3,4-d]pyrimidin-3-one
Recommended Storage	Store at -20°C
Molecular Formula	C₂₇H₃₂N₈O₂

MedChemExpress Adavosertib (AZD-1775; MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM.

Molecular Weight (g/mol)	500.6
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Adavosertib
Grade	Research
SMILES	O=C1N(N(C2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C21)C5=NC(C(O)(C)C)=CC=C5)CC=C
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.59%
CAS	955365-80-7
Solubility Information	DMSO : 125 mg/mL (249.70 mM; Need ultrasonic)
Health Hazard 1	H315∣H319∣H335
Synonym	AZD1775 MK-1775
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₃₂N₈O₂
Formula Weight	500.6