CAS RN 912545-86-9

CAS RN 912545-86-9

IUPAC Name: 3-chloro-N-[4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide

Synonyms: smoothened agonist

Molecular Weight (g/mol): 490.06

Molecular Formula: C28H28ClN3OS

InChi Key: VFSUUTYAEQOIMW-UHFFFAOYSA-N

SMILES: CNC1CCC(CC1)N(CC1=CC(=CC=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1

Molecular Weight (g/mol)

1 – 3 of 3 results

1

Thermo Scientific™ SAG

Pricing and Availability

2

STEMCELL Technologies SAG

Hedgehog pathway activator; Activates Smoothened (SMO)

ENCOMPASS_PREFERRED

Pricing and Availability
Specifications

CAS	912545-86-9
Purity	≥98%
Synonym	Smoothened Agonist
Molecular Formula	C₂₈H₂₈ClN₃OS

3

SAG, MedChemExpress

MedChemExpress SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo.

ENCOMPASS_PREFERRED

Pricing and Availability
Specifications

Molecular Weight (g/mol)	490.06
Color	Off-White
Physical Form	Solid
Chemical Name or Material	SAG
Grade	Research
SMILES	O=C(C1=C(Cl)C2=CC=CC=C2S1)N([C@H]3CC[C@H](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.51%
CAS	912545-86-9
Solubility Information	DMSO : ≥ 38 mg/mL (77.54 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula	C₂₈H₂₈ClN₃OS
Formula Weight	490.06