CAS RN 1627709-94-7
CAS RN 1627709-94-7
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Tocris Bioscience™ LJI308
Potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM)
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LJI308, MedChemExpress
MedChemExpress LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.
