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TRA-1-60 (Podocalyxin) Monoclonal Antibody (TRA-1-60), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-8863-95

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Product Code. 17100692

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Description

Description

The TRA-1-60 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embyronal carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-60 antibody is lost upon cell differentiation. Contrary to early reports that the TRA-1-60 epitope can be destroyed by neuraminidase digestion, new strudies have shown that TRA-1-60 recognizes a neurominidase resistent antigen. The TRA-1-60 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.

TRA-1-60 (Podocalyxin) Monoclonal antibody specifically detects TRA-1-60 (Podocalyxin) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRA-1-60 (Podocalyxin)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Mouse
10 mg
Primary
4° C
Liquid
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
TRA-1-60
Unconjugated
TRA160; tra60
Affinity chromatography
RUO
Human
Antibody
IgM
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