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TNFRSF6B Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24999-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893515

  • 3468.15 NOK / 150µL
Estimated Shipment: 19-12-2022
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Description

Description

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
Specifications

Specifications

TNFRSF6B
Polyclonal
Unconjugated
TNFRSF6B
DCR3, Decoy receptor 3, Decoy receptor for Fas ligand, M68, TNFRSF6B, TR6
Rabbit
Antigen Affinity Chromatography
RUO
8771
-20°C
Liquid
Immunoprecipitation
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O95407
TNFRSF6B
TNFRSF6B Fusion Protein Ag19781
150 μL
Primary
Human
Antibody
IgG
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