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ACROBiosystems SARS-CoV-2 (COVID-19) S1 protein (N501Y), His Tag

Brand:  ACROBiosystems S1N-C52Hg-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 17206470

  • 5751.64 NOK / 100µg

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Description

Description

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.9 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

QHD43416.1 (N501Y)
100 µg
Val 16 - Arg 685
Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,COVID-19
Unconjugated
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
>90% as determined by SDS-PAGE.
76.9 kDa
SARS-CoV-2 S1 protein (N501Y), His Tag (S1N-C52Hg) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (N501Y)). N501Y mutaion was identified in both the SARS-CoV-2 variant (known as 20 B/501 Y.V1, VOC 202012/01, or B0.1.1.7 lineage) which emerged in the United Kindom and SARS-CoV-2 variant (known as 20 C/501 Y.V2 or B0.1.351 lineage) which emerged in South Africa.
-20°C
S1 protein
SARS-CoV-2
PBS, pH7.4
HEK293
Viral Proteins
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