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Invitrogen™ Rat TNF R1 ELISA Kit
Rat TNF R1 quantitates rat TNF R1 in serum, plasma, supernatant.
Brand: Invitrogen™ ERA55RB
Additional Details : Weight : 0.33820kg
Description
Rat TNF R1 quantitates rat TNF R1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat TNF R1.
TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.Specifications
| CD120a; CD120a antigen; FPF; hypothetical protein; LOC100346106; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TNF receptor alpha chain; TNF receptor superfamily member 1 A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; TNFRSF1A; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1 A isoform beta; tumor necrosis factor receptor 1-like; tumor necrosis factor receptor superfamily member 1 A; Tumor necrosis factor receptor superfamily member 1 A, membrane form; tumor necrosis factor receptor superfamily, member 1 A; tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis | |
| 2 pg/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| Tnfrsf1a | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 2 to 600 pg/mL | |
| Biotin | |
| Serum, Plasma, Supernatant | |
| P22934 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 96 Tests | |
| Supernatant, 50 µL; Plasma, 50 µL; Serum, 50 µL | |
| TNFR1 | |
| 4 hr 45 min |