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Thermo Scientific™ DTME (dithiobismaleimidoethane)

Product Code. 10371314 Shop All Thermo Scientific Products
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Quantity:
50 mg
Unit Size:
50mg
Product Code. Quantity unitSize
10371314 50 mg 50mg
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Product Code. 10371314

Brand: Thermo Scientific™ 22335

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Description

Crosslink sulfhydryls to sulfhydryls (cysteine residues) with this long, cleavable crosslinker composed of maleimide groups and 11-atom (13.3A) disulfide spacer arm.

Thermo Scientific™ Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide cysteines) by reduction of the disulfide bond in the center of the spacer arm.

Highlights:

  • Cleavable by reducing agents
  • Reactive groups: maleimide (homobifunctional)
  • Reactive toward: sulfhydryl groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Sulfhydryl-Sulfhydryl
Cleavable By Thiols
Description DTME
Molecular Weight (g/mol) 312.36
PEGylated No
Spacer Arm Length 13.3 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Maleimide
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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Safety and Handling

compliance-icons
Product Identifier
  • DTME (dithiobismaleimidoethane)
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H312-Harmful in contact with skin.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : Dithio-BisMaleimidoethane

For Research Use Only. Not for use in diagnostic procedures.

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