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Invitrogen™ Human ULBP-1 ELISA Kit
Human ULBP-1 quantitates human ULBP-1 in serum, plasma, supernatant.
Brand: Invitrogen™ EH476RBX5
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Description
Human ULBP-1 quantitates human ULBP-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ULBP-1.
ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Specifications
| A430108B07Rik; ALCAN-beta; MULT1; N2DL1; N2DL-1; NKG2D ligand; NKG2D ligand 1; NKG2D ligand1; NKG2DL1; RAET1I; Retinoic acid early transcript 1 I; UL16 binding protein 1; UL16-binding protein 1; UL16-binding protein-like transcript 1; ULBP; ULBP 1; Ulbp1 | |
| 0.4 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| ULBP1 | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 0.4 to 100 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| Q9BZM6 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 5 x 96 Tests | |
| Serum, 50 μL; Supernatant, 50 μL; Plasma, 50 μL | |
| ULBP1 | |
| 4 hr 45 min |