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ACROBiosystems Human DcR3 / TNFRSF6B Protein, Fc Tag

Brand:  ACROBiosystems TNB-H5255-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 16448109

  • 34828.76 NOK / 1mg
Estimated Shipment: 23-01-2023
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Description

Description

Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.2 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

AAH17065
56.2 kDa
1 mg
Val 30 - His 300
TNFRSF6B,DCR3,TR6,M68
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human DcR3, Fc Tag (TNB-H5255) is expressed from human 293 cells (HEK293). It contains AA Val 30 - His 300 (Accession # O95407-1).
-20°C
DcR3
Fc Tag
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
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