Learn More
ACROBiosystems Human DcR3 / TNFRSF6B Protein, Fc Tag
Brand: ACROBiosystems TNB-H5255-1mg
Additional Details : Weight : 0.00010kg
Description
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.2 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
AAH17065 | |
1 mg | |
Val 30 - His 300 | |
TNFRSF6B,DCR3,TR6,M68 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
56.2 kDa | |
Human DcR3, Fc Tag (TNB-H5255) is expressed from human 293 cells (HEK293). It contains AA Val 30 - His 300 (Accession # O95407-1). | |
-20°C | |
DcR3 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Other Recombinant Proteins |