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Invitrogen™ Human Caspase-1 ELISA Kit

Product Code. 16895441
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Quantity:
5 x 96 Tests
96 Tests
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Each
Product Code. Quantity unitSize
16895441 96 Tests Each
17195299 5 x 96 Tests Each
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Product Code. 16895441

Brand: Invitrogen™ EH70RB

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ELISA

Human Caspase-1 quantitates human Caspase-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Caspase-1.

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1 B converting enzyme; IL1BC; IL-1 BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1 beta converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
Assay Range 0.43 to 100 ng/mL
Assay Sensitivity 0.43 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 834
Gene Symbol CASP1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Caspase 1
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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