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FLJ14213 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 26355-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.Specifications
FLJ14213 | |
Polyclonal | |
Unconjugated | |
PRR5L | |
FLJ14213, Proline rich protein 5 like, Protein observed with Rictor 2, protor 2, PROTOR2, PRR5L | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
79899 | |
-20°C | |
Liquid |
Western Blot | |
0.51 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q6MZQ0 | |
PRR5L | |
FLJ14213 Fusion Protein Ag23837 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |