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E2A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21242-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16890855

  • 1281.92 NOK / 20µL
Estimated Shipment: 19-12-2022
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Description

Description

TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5′- CANNTG-3′. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Specifications

Specifications

E2A
Polyclonal
Unconjugated
TCF3
bHLHb21, E2A, E47, ITF1, Kappa E2 binding factor, TCF 3, TCF3, Transcription factor 3, Transcription factor E2 alpha, Transcription factor ITF 1
Rabbit
Antigen Affinity Chromatography
RUO
171046, 21423, 6929
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.6 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P15806, P15923, P21677
Tcf3
E2A Fusion Protein Ag15734
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
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