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Cytohesin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16687-1-AP-20UL

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Product Code. 16896394

  • 1696.32 NOK / 20µL

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Description

Description

GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain as well as a Sec7 domain. The PH domain has high binding affinity for phosphatidylinositol 3,4,5-trisphosphate Ptdlns(3,4,5)P3), while the Sec7 homology domain is responsible for catalyzing guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins. GRP1 co-localizes with ARF6 and catalyzes GTP/GDP exchange on ARF6. It is known to interact with Ptdlns(3,4,5)P3 localized to the plasma membrane in vitro and may also be a Ptdlns(3,4,5)P3 receptor. Additionally, GRP1 may regulate protein sorting and membrane trafficking through interaction with the guanosine triphosphate ARF, and may control cell adhesion through interaction with integrins.
Specifications

Specifications

Cytohesin 3
Polyclonal
Unconjugated
CYTH3
ARNO3, CYTH3, cytohesin 3, GRP1, Protein ARNO3, PSCD3
Rabbit
Antigen Affinity Chromatography
RUO
116693, 19159, 9265
-20°C
Liquid
Western Blot
0.48 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O08967, O43739, P97696
Cyth3
Cytohesin 3 Fusion Protein Ag10025
20 μL
Primary
Rat, Human, Mouse
Antibody
IgG
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