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ACROBiosystems Cynomolgus Nectin-4 Protein, His Tag

Brand:  ACROBiosystems NE4-C52H4-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 16447909

  • 32169.11 NOK / 1mg
Estimated Shipment: 16-01-2023
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Description

Description

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

XP_005541277.1
36.0 kDa
1 mg
Gly 32 - Ser 349
NECTIN4,LNIR, PRR4, PVRL4
Unconjugated
PBS, pH7.4
HEK293
Cynomolgus
Powder
>95% as determined by SDS-PAGE
Cynomolgus Nectin-4, His Tag (NE4-C52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # XP_005541277.1).
-20°C
Nectin-4
His Tag
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
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