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ACROBiosystems Cynomolgus Nectin-4 Protein, His Tag

5341.70 NOK - 39223.36 NOK

Specifications

Accession Number XP_005541277.1
Molecular Weight (g/mol) 36.0 kDa
Source Cynomolgus Nectin-4, His Tag (NE4-C52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # XP_005541277.1).
Immunogen Gly 32 - Ser 349
Storage Requirements -20°C
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
16437909
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ACROBiosystems
NE4-C52H4-100UG
100 μg
5341.70 NOK
100µg
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16447909
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ACROBiosystems
NE4-C52H4-1MG
1 mg
39223.36 NOK
1mg
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Estimated Shipment: 02-05-2024
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Description

Description

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

XP_005541277.1
Cynomolgus Nectin-4, His Tag (NE4-C52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # XP_005541277.1).
-20°C
Nectin-4
Cynomolgus Monkey
PBS, pH7.4
HEK293
Immune Checkpoint Proteins
36.0 kDa
Gly 32 - Ser 349
NECTIN4,LNIR, PRR4, PVRL4
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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