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CD154 (CD40 Ligand) Monoclonal Antibody (MR1), Functional Grade, eBioscience™, Invitrogen™
Armenian Hamster Monoclonal Antibody
30070.00 NOK - 150400.00 NOK
Specifications
| Antigen | CD154 (CD40 Ligand) |
|---|---|
| Clone | MR1 |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Neutralization |
| Classification | Monoclonal |
Description
The MR1 MAb reacts with mouse CD154, a 39 kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle. For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.
CD154 (CD40 Ligand) Monoclonal antibody specifically detects CD154 (CD40 Ligand) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, NeutralizationSpecifications
| CD154 (CD40 Ligand) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; Cd40l; CD40-L; CD40LG; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; Tnfsf5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5 | |
| IgG | |
| Affinity chromatography | |
| Antibody |
| MR1 | |
| Flow Cytometry, Functional Assay, Neutralization | |
| Functional Grade | |
| Armenian Hamster | |
| Mouse | |
| P27548 | |
| 21947 | |
| Primary | |
| 4° C | |
| CD40LG |
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