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  7. 17191162

CD154 (CD40 Ligand) Monoclonal Antibody (MR1), Functional Grade, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-1541-050

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Product Code. 17191162

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Description

Description

The MR1 MAb reacts with mouse CD154, a 39 kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle. For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.

CD154 (CD40 Ligand) Monoclonal antibody specifically detects CD154 (CD40 Ligand) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD154 (CD40 Ligand)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P27548
Armenian Hamster
50 mg
Primary
Mouse
Antibody
IgG
Flow Cytometry, Functional Assay, Neutralization
MR1
Functional Grade
CD40LG
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; Cd40l; CD40-L; CD40LG; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; Tnfsf5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Affinity chromatography
RUO
21947
4° C
Liquid
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